Biology
We study function and regulation of proteins related to ubiquitin in cellular processes of pre-messenger RNA splicing and signaling. For these studies, we perform experiments in molecular cell biology, genetics, and biochemistry in the budding yeast Saccharomyces cerevisiae and fission yeast Schizosaccharomyces pombe. We use mammalian cell cultures and multi-cellular organisms through collaborations to highlight relevance of our findings in humans.